Midnight Run (1988)

Robert DeNiro is a Los Angeles bounty hunter hired to bring in Chicago mob accountant Charles Grodin. What should have been an easy job becomes a cross-country road trip with the two being followed by mob enforcers, the FBI, and another bounty hunter trying to get in on the score. Grodin plays a cunning, neurotic mess with De Niro coming behind at every step. The whole affair is an amusing buddy comedy with a supporting cast that includes Yaphet Kotto, Joe Pantoliano, and Philip Baker Hall.